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Leading the way in Alzheimer’s disease research

The Australian Imaging, Biomarker and Lifestyle (AIBL) Flagship Study of Ageing is an ongoing observational cohort study helping researchers unlock new insights into the onset and progression of Alzheimer’s disease.

The AIBL study collects information from the cohort every 18 months on biomarkers (proteins related to Alzheimer’s disease) from blood and cerebrospinal fluid and nuclear and structural neuroimaging methods. Our researchers also collect information about cognition, mood and health and lifestyle factors that determine the development of Alzheimer’s disease.

Since 2006, AIBL has collected study data from 3045* participants with 10,494* person-contact years. This large database of highly characterised individuals has provided a foundation for clinical pathological models of the development of Alzheimer’s disease, for characterising clinical and biological changes in the early or preclinical stage of Alzheimer’s disease and for the design of medicines aimed at delaying the onset, preventing and treating Alzheimer’s disease.

*at February 2023

about us

How AIBL works

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Well established

Launched on 14 November 2006

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15+ year longitudinal study of cognition with replenishment recruitment

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Large cohort

3000+ participants (minimum age 50 years)

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Clear Goals

Focus on early detection, towards lifestyle interventions and early dementia prevention treatments

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Varied Participants

Alzheimer’s disease, mild cognitive impairment and healthy participants

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Solid Support

Founding support from CSIRO and the CSIRO Science and Industry Endowment Fund

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Study data is collected at our two centres in Perth and Melbourne. Our multidisciplinary research team is drawn from partnership organisations, primarily based in Melbourne, Perth and Brisbane.

  • Data collection centres
  • All research centres
Our Work

Six streams of research

The AIBL study comprises six research streams, which help increase our value, impact and productivity.

Contribute To Alzheimer’s Disease Research

Get involved

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Information for current and new research volunteers.
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Information for current and new researchers and other collaborators.

News and events

Get the latest global news about dementia research.


Explore innovations and clinical developments in Alzheimer’s disease.

Partners and supporters

Australian Alzheimer's Research Foundation logo in purple.
Austin Health logo in full colour.
CSIRO logo white text on a light blue circle background.
Dementia Collaborative Research Centres (DCRC) logo with black text and blue logo mark consisting of three connected circles.
Edith Cowan University logo in full colour - navy blue, yellow, red and white text.
The University of Melbourne stacked logo with Greek goddess of victory, Nike, logomark in blue and white. Logo text reads: 'Postera crescam laude' - a promise to 'grow in the esteem of future generations.'
The Florey logo in all black, with text reading 'Advancing Brain Research' underneath the logo text.
Sir Charles Gairdner Hospital logo with white text and New South Wales coat of arms logo mark. Logo text reads: 'Government of Western Australia North Metropolitan Health Service Sir Charles Gairdner Hospital'.
Hollywood Private Hospital stacked logo with navy blue text.
Macquarie University, Sydney Australia stacked logo in full colour. Logo text is in black and lighthouse logomark is white on a red and burgundy background.
National Ageing Research Institute (NARO) logo in full colour (blue and green). Logo tagline underneath logo text reads: 'Bringing research to life'.
The University of Western Australia logo with blue text and a yellow and white swan coat of arms logomark. Text reads: 'seek wisdom.'
Fight Alzheimer's Save Australia logo with green and black text, including URL text ''.

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